Description

tert-Butyl 2,4-Dihydroxy-5H,6H,7H,8H-Pyrido[4,3-D]Pyrimidine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused pyrido-pyrimidine heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and antiviral research.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel small-molecule drugs, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Used in the preparation of complex heterocyclic compounds for academic and industrial research purposes.
• Biochemical Reagent: Potential use as a reference standard or a tool compound in biochemical and pharmacological assays.

Basic Information

Product Name	tert-Butyl 2,4-Dihydroxy-5H,6H,7H,8H-Pyrido[4,3-D]Pyrimidine-6-Carboxylate
CAS No.	880257-39-6
Molecular Formula	C₁₂H₁₇N₃O₄
Molecular Weight	267.28 g/mol
Synonyms	6-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4-diol; tert-Butyl 2,4-dihydroxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-6-carboxylate; 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine-2,4-diol, 6-[(1,1-dimethylethoxy)carbonyl]-; 880257-39-6; Pyrido[4,3-d]pyrimidine-6-carboxylic acid, 2,4-dihydroxy-5,6,7,8-tetrahydro-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,4-Dihydroxy-5H,6H,7H,8H-Pyrido[4,3-D]Pyrimidine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.