Description

4-Carboxy-Tryptophan is a modified amino acid derivative of tryptophan, featuring a carboxylic acid functional group at the 4-position of the indole ring. This structural modification makes it a valuable non-natural amino acid and a critical building block for advanced research and development in pharmaceutical chemistry. It is primarily sought after by researchers and manufacturers in the life sciences sector for its role in peptide synthesis and biochemical studies. The compound is supplied under strict quality control to ensure consistency for sensitive applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel peptide-based therapeutics and drug candidates.
• Biochemical Research: Used as a specialized reagent in enzymatic studies, metabolic pathway analysis, and protein engineering.
• Peptide Synthesis: Incorporated into custom peptides as a modified amino acid to alter physicochemical properties or introduce specific functional handles.
• Proteomics & Mass Spectrometry: Can be used as a standard or a labeled analog in quantitative proteomic analysis and mass spectrometry calibration.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	4-Carboxy-Tryptophan
CAS No.	879553-00-1
Molecular Formula	C12H12N2O4
Molecular Weight	248.23 g/mol
Synonyms	4-Carboxy-DL-tryptophan; 4-Carboxytryptophan; 1H-Indole-4-carboxylic acid, 2-amino-3-(1H-indol-3-yl)-; Tryptophan, 4-carboxy-; 2-Amino-3-(4-carboxy-1H-indol-3-yl)propanoic acid; (RS)-2-Amino-3-(4-carboxy-1H-indol-3-yl)propanoic acid; DL-4-Carboxytryptophan
EINECS	Contact for details

Quality Control

Every batch of 4-Carboxy-Tryptophan is produced and analyzed under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.