Description

2-(4-Fluorophenyl)Cyclopropanamine Hydrochloride is a high-purity, pharmaceutically relevant organic building block supplied as a hydrochloride salt for enhanced stability. This compound serves as a critical chiral intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry, particularly for projects targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to explore novel pharmacophores.
• API Synthesis: Employed in the scalable production of advanced intermediates for potential Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Serves as a precursor for labeled compounds or probes used in pharmacological and biochemical assays.
• Asymmetric Synthesis: Utilized in chiral pool synthesis due to its rigid cyclopropane ring structure, which can impart conformational constraint to target molecules.

Basic Information

Product Name	2-(4-Fluorophenyl)Cyclopropanamine Hydrochloride
CAS No.	879396-75-5
Molecular Formula	C9H11FN • HCl
Molecular Weight	187.65 g/mol (Free base: 151.19 g/mol)
Synonyms	1-(4-Fluorophenyl)cyclopropanamine hydrochloride; (1-(4-Fluorophenyl)cyclopropyl)amine hydrochloride; 2-(4-Fluorophenyl)cyclopropylamine HCl; 4-Fluorophenylcyclopropylamine hydrochloride; trans-2-(4-Fluorophenyl)cyclopropanamine hydrochloride; 1-Amino-1-(4-fluorophenyl)cyclopropane hydrochloride; 879396-75-5; FCYA hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)Cyclopropanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR, and mass spectrometry for structural confirmation, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.