Description

2,5-Difluoro-4-Methoxybenzaldehyde is a high-purity fluorinated aromatic aldehyde building block. This compound is valued for its unique substitution pattern, which imparts specific electronic and steric properties critical for advanced synthesis. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in medicinal chemistry for lead optimization and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates targeting CNS disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro-methoxy motif can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and as a precursor for heterocyclic compounds like benzimidazoles and quinazolines in academic and industrial R&D.
• Fluorinated Dye & Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where fluorine atoms improve lightfastness and alter chromatic properties.

Basic Information

Product Name	2,5-Difluoro-4-Methoxybenzaldehyde
CAS No.	879093-08-0
Molecular Formula	C8H6F2O2
Molecular Weight	172.13 g/mol
Synonyms	4-Methoxy-2,5-difluorobenzaldehyde; 2,5-Difluoro-4-methoxybenzaldehyde; 2,5-Difluoro-p-anisaldehyde; Benzaldehyde, 2,5-difluoro-4-methoxy-; 879093-08-0; 4-Methoxy-2,5-difluorobenzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-4-Methoxybenzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.