Description

4-Dimethoxymethyl-2-Trifluoromethyl-Pyrimidine is a high-value, multi-functional pyrimidine derivative characterized by its dimethoxymethyl and trifluoromethyl substituents, which confer unique reactivity and stability. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Material Science Precursor: Employed in the research and development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D for constructing complex heterocyclic compounds and fluorinated molecules.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	4-Dimethoxymethyl-2-Trifluoromethyl-Pyrimidine
CAS No.	878760-47-5
Molecular Formula	C8H9F3N2O2
Molecular Weight	222.17 g/mol
Synonyms	2-Trifluoromethyl-4-dimethoxymethylpyrimidine; 4-(Dimethoxymethyl)-2-(trifluoromethyl)pyrimidine; Pyrimidine, 4-(dimethoxymethyl)-2-(trifluoromethyl)-; 4-Dimethoxymethyl-2-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Dimethoxymethyl-2-Trifluoromethyl-Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support development and commercial projects requiring compliance with various pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.