Description

Methyl 2-Trifluoromethyl-4-Pyrimidine Carboxylate is a high-value fluorinated pyrimidine building block essential for advanced organic synthesis. This compound is critical for introducing the 2-trifluoromethylpyrimidine-4-carboxylate moiety, a key pharmacophore known to enhance metabolic stability and binding affinity in drug candidates. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas, including oncology and antiviral treatments.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental persistence.
• Material Science: Serves as a specialized monomer or additive in the research of advanced polymers and liquid crystals with unique electronic or optical properties.
• Chemical Synthesis: Acts as a versatile building block for constructing complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Diagnostic Reagents: Potential use in the synthesis of probes and labeling agents for biochemical assays and imaging.

Basic Information

Product Name	Methyl 2-Trifluoromethyl-4-Pyrimidine Carboxylate
CAS No.	878745-51-8
Molecular Formula	C7H5F3N2O2
Molecular Weight	206.12 g/mol
Synonyms	Methyl 2-(trifluoromethyl)pyrimidine-4-carboxylate; 2-Trifluoromethyl-4-pyrimidinecarboxylic acid methyl ester; 4-Pyrimidinecarboxylic acid, 2-(trifluoromethyl)-, methyl ester; Methyl 2-trifluoromethylpyrimidine-4-carboxylate; 2-(Trifluoromethyl)pyrimidine-4-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Trifluoromethyl-4-Pyrimidine Carboxylate adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.