Description

5-Methyl-4-Oxo-3-Propyl-3,4-Dihydro-Thieno[2,3-D]-Pyrimidine-6-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS number 878657-13-7. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its precise molecular architecture that enables the synthesis of targeted therapeutic agents. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly in areas requiring complex fused-ring systems.

Application

This specialized intermediate serves as a key precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core scaffold for the synthesis of potential kinase inhibitors and other biologically active molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Chemical Biology Probes: Employed in the creation of tool compounds for studying specific enzyme functions and cellular pathways.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	5-Methyl-4-Oxo-3-Propyl-3,4-Dihydro-Thieno[2,3-D]-Pyrimidine-6-Carboxylic Acid
CAS No.	878657-13-7
Molecular Formula	C11H12N2O3S
Molecular Weight	252.29 g/mol
Synonyms	Thieno[2,3-d]pyrimidine-6-carboxylic acid, 3,4-dihydro-5-methyl-4-oxo-3-propyl-; 3-Propyl-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic acid; 878657-13-7; 5-Methyl-3-propyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all critical quality attributes. We support compliance with cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.