Description

5-Ethyl-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid is a high-value, heterocyclic carboxylic acid building block critical for advanced organic synthesis. Its unique pyrazolopyrimidine core, combined with ethyl and trifluoromethyl substituents, makes it an essential intermediate for developing novel bioactive molecules. This compound is primarily sought after by pharmaceutical and agrochemical R&D teams for the creation of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel small-molecule drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used in the research and synthesis of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazolopyrimidine scaffold.
• Chemical Biology Probe Synthesis: Serves as a core structure for creating specialized probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a precursor for advanced organic materials and ligands in catalytic systems.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and library production for high-throughput screening.

Basic Information

Product Name	5-Ethyl-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid
CAS No.	878618-88-3
Molecular Formula	C₁₁H₁₂F₃N₃O₂
Molecular Weight	275.23 g/mol
Synonyms	5-Ethyl-7-(trifluoromethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 5-Ethyl-7-trifluoromethyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid; 878618-88-3; Pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 4,5,6,7-tetrahydro-5-ethyl-7-(trifluoromethyl)-; 5-Ethyl-7-trifluoromethyl-4,5,6,7-tetrahydro-2H-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-Ethyl-7-Trifluoromethyl-4,5,6,7-Tetrahydro-Pyrazolo[1,5-A]Pyrimidine-2-Carboxylic Acid adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.