Description

2-Amino-5-[3-Methoxy-4-(Prop-2-En-1-Yloxy)Phenyl]-3H,4H,5H,6H,7H,8H-Pyrido[2,3-D]Pyrimidine-4,7-Dione is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a key building block in the synthesis of novel therapeutic agents, particularly in oncology and targeted drug development. It is primarily required by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of innovative small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Biochemical Research: Acts as a tool compound for studying enzyme inhibition and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic and medicinal chemistry.

Basic Information

Product Name	2-Amino-5-[3-Methoxy-4-(Prop-2-En-1-Yloxy)Phenyl]-3H,4H,5H,6H,7H,8H-Pyrido[2,3-D]Pyrimidine-4,7-Dione
CAS No.	878437-15-1
Molecular Formula	C19H20N4O4
Molecular Weight	368.39 g/mol
Synonyms	2-Amino-5-[3-methoxy-4-(prop-2-en-1-yloxy)phenyl]-3,4,5,6,7,8-hexahydropyrido[2,3-d]pyrimidine-4,7-dione; 2-Amino-5-(3-methoxy-4-allyloxyphenyl)-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine-4,7(3H)-dione; Allyloxy-methoxyphenyl-pyridopyrimidinedione derivative; CAS 878437-15-1; Pyrido[2,3-d]pyrimidine-4,7-dione derivative; Advanced kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our 2-Amino-5-[3-Methoxy-4-(Prop-2-En-1-Yloxy)Phenyl]-3H,4H,5H,6H,7H,8H-Pyrido[2,3-D]Pyrimidine-4,7-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines for pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.