Description

3,5-Difluoro-4-Methylaniline is a fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the introduction of fluorine atoms and an aniline functionality, which are pivotal for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, where the fluorine atoms enhance lipophilicity and environmental stability.
• Liquid Crystal & Electronic Materials: Used in the synthesis of fluorinated aromatic components for liquid crystal displays (LCDs) and organic semiconductors.
• Dye & Pigment Manufacturing: Intermediate for producing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
• Polymer Modification: Incorporation into polymer backbones to impart specific chemical resistance, thermal stability, or surface properties.
• Research & Development: Versatile reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways in medicinal and materials chemistry.

Basic Information

Product Name	3,5-Difluoro-4-Methylaniline
CAS No.	878285-13-3
Molecular Formula	C7H7F2N
Molecular Weight	143.13 g/mol
Synonyms	4-Methyl-3,5-difluoroaniline; 3,5-Difluoro-p-toluidine; 3,5-Difluoro-4-methylbenzenamine; Benzenamine, 3,5-difluoro-4-methyl-; 4-Amino-2,6-difluorotoluene; 2,6-Difluoro-4-methylaniline; 3,5-Difluoro-4-methyl-phenylamine
EINECS	Contact for details

Quality Control

Our production of 3,5-Difluoro-4-Methylaniline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.