Description

n-(3-Chloro-4-Methoxyphenyl)-1-Methyl-6-(Morpholin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of targeted kinase inhibitors and other biologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutics for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent and selective kinase inhibitors for drug discovery programs.
• Oncology Research: Used in the development of investigational new drugs (INDs) targeting specific cancer pathways.
• Biochemical Tool Compound: Serves as a reference standard or a core scaffold for structure-activity relationship (SAR) studies in medicinal chemistry.
• API Synthesis: Employed in the pilot-scale and commercial-scale manufacturing of active pharmaceutical ingredients (APIs) for clinical trials and production.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs and CROs specializing in custom synthesis and process development for clients.

Basic Information

Product Name	n-(3-Chloro-4-Methoxyphenyl)-1-Methyl-6-(Morpholin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine
CAS No.	878063-62-8
Molecular Formula	C17H19ClN6O2
Molecular Weight	374.82 g/mol
Synonyms	1-Methyl-6-(morpholin-4-yl)-N-[3-chloro-4-methoxyphenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 6-Morpholino-1-methyl-N-(3-chloro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 878063-62-8; UNII-9J2B8T6F8Q; 9J2B8T6F8Q; BDBM50142441; AKOS025310923; ZINC000004169777; CHEMBL3185143
EINECS	Contact for details

Quality Control

Our production of n-(3-Chloro-4-Methoxyphenyl)-1-Methyl-6-(Morpholin-4-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine adheres to stringent quality systems suitable for pharmaceutical development. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications and results from techniques including HPLC, NMR, and MS is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.