Description

(E)-2-Methoxy-6-((2-(5-Phenylthieno[2,3-D]Pyrimidin-4-Yl)Hydrazono)Methyl)Phenol is a high-purity, advanced pharmaceutical intermediate characterized by its unique thienopyrimidine-hydrazone-phenol hybrid structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel small molecule therapeutics targeting various disease pathways. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing kinase inhibitors, anticancer agents, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel thieno[2,3-d]pyrimidine-based drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold in the development of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry & SAR Studies: Used extensively in structure-activity relationship (SAR) studies to optimize drug-like properties and biological activity.
• Biochemical Probe Development: Utilized in creating chemical probes for target identification and validation in cellular pathways.
• Contract Research & Development: Supplied to CROs and CDMOs for custom synthesis and pre-clinical development projects.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and drug discovery.

Basic Information

Product Name	(E)-2-Methoxy-6-((2-(5-Phenylthieno[2,3-D]Pyrimidin-4-Yl)Hydrazono)Methyl)Phenol
CAS No.	877792-12-6
Molecular Formula	C20H16N4O2S
Molecular Weight	376.44 g/mol
Synonyms	(E)-2-Methoxy-6-((2-(5-Phenylthieno[2,3-d]pyrimidin-4-yl)hydrazineylidene)methyl)phenol; 2-Methoxy-6-[(E)-[2-(5-phenylthieno[2,3-d]pyrimidin-4-yl)hydrazinylidene]methyl]phenol; Phenol, 2-methoxy-6-[(E)-[2-(5-phenylthieno[2,3-d]pyrimidin-4-yl)hydrazinylidene]methyl]-; Thienopyrimidine Hydrazone Derivative; 5-Phenylthieno[2,3-d]pyrimidin-4-yl Hydrazone; CAS 877792-12-6
EINECS	Contact for details

Quality Control

Our (E)-2-Methoxy-6-((2-(5-Phenylthieno[2,3-D]Pyrimidin-4-Yl)Hydrazono)Methyl)Phenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.