Description

(R)-2-Chloro-7-Ethyl-8-Isopropyl-5-Methyl-7,8-Dihydropteridin-6(5H)-One is a high-purity, chiral pteridine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or building block for synthesizing novel, targeted therapeutic agents. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers working in drug discovery programs, particularly those focused on enzyme inhibition and pathway modulation.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research-scale synthesis of potential drug candidates targeting specific biological pathways.
• Biochemical Research: Used as a reference standard or probe molecule in enzymatic studies and mechanism-of-action investigations.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic chemistry and heterocyclic compound behavior.

Basic Information

Product Name	(R)-2-Chloro-7-Ethyl-8-Isopropyl-5-Methyl-7,8-Dihydropteridin-6(5H)-One
CAS No.	877676-50-1
Molecular Formula	C12H17ClN4O
Molecular Weight	268.74 g/mol
Synonyms	(R)-2-Chloro-7-ethyl-8-(propan-2-yl)-5-methyl-7,8-dihydro-5H-pteridin-6-one; (6R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydro-5H-pteridin-6-one; (R)-2-Chloro-7-ethyl-8-isopropyl-5-methyl-5,6,7,8-tetrahydropteridin-6-one; 877676-50-1; UNII-9F6K0J1J0H; 9F6K0J1J0H; (R)-enantiomer of 2-Chloro-7-ethyl-8-isopropyl-5-methyl-7,8-dihydropteridin-6(5H)-one
EINECS	Contact for details

Quality Control

Our production of (R)-2-Chloro-7-Ethyl-8-Isopropyl-5-Methyl-7,8-Dihydropteridin-6(5H)-One adheres to stringent in-process controls and final release testing to ensure consistent identity, purity, and chiral integrity. Quality is verified via advanced analytical techniques including HPLC, GC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.