Description

2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-f]pyrimidin-5-ol is a high-value heterocyclic building block containing both a trifluoromethyl group and a fused triazolopyrimidine core. This compound is prized for its unique electronic properties and structural complexity, which make it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas like kinase inhibitors and antiviral agents.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the triazolopyrimidine scaffold.
• Material Science: Serves as a precursor for specialty chemicals and functional materials, including ligands for catalysis.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development within university and CRO laboratories.
• Fluorinated Compound Synthesis: The presence of the trifluoromethyl group makes it valuable for introducing fluorine into target molecules to modulate their properties.

Basic Information

Product Name	2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-f]pyrimidin-5-ol
CAS No.	877402-88-5
Molecular Formula	C6H2F3N5O
Molecular Weight	217.11 g/mol
Synonyms	2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-5-ol; 2-(Trifluoromethyl)-1,2,4-triazolo[1,5-f]pyrimidin-5-ol; 5-Hydroxy-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-f]pyrimidine; 2-(Trifluoromethyl)-1,2,4-triazolo[1,5-a]pyrimidin-5(4H)-one (tautomer); 877402-88-5; 2-Trifluoromethyl-[1,2,4]triazolo[1,5-f]pyrimidin-5-ol
EINECS	Contact for details

Quality Control

Our production of 2-(Trifluoromethyl)-[1,2,4]triazolo[1,5-f]pyrimidin-5-ol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for assay and purity determination. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.