Description

tert-Butyl 3-(3-Bromo-7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate of significant importance in modern drug discovery. This compound serves as a critical building block for the synthesis of novel, potent kinase inhibitors and other biologically active molecules. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing targeted therapies for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors targeting various disease pathways.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Chemical Biology Research: Employed as a molecular probe to study enzyme function and cellular signaling mechanisms.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Process Chemistry: Utilized in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	tert-Butyl 3-(3-Bromo-7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate
CAS No.	877173-82-5
Molecular Formula	C16H18BrClN4O2
Molecular Weight	413.70 g/mol
Synonyms	1-Boc-3-(3-bromo-7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine; tert-Butyl 3-(3-bromo-7-chloro-pyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate; 3-(3-Bromo-7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylic acid tert-butyl ester; 877173-82-5; 1-(tert-Butoxycarbonyl)-3-(3-bromo-7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine; Boc-3-(3-bromo-7-chloro-pyrazolo[1,5-a]pyrimidin-5-yl)piperidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-(3-Bromo-7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.