Description

tert-Butyl 3-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and contract research organizations (CROs) focused on drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors and other small molecule therapeutics.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry & Scale-Up: Serves as a defined intermediate for the commercial-scale synthesis of target APIs under cGMP conditions.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying biological pathways and target engagement.
• Custom Synthesis: Employed by fine chemical suppliers for the custom manufacturing of client-specific molecular entities.

Basic Information

Product Name	tert-Butyl 3-(7-Chloropyrazolo[1,5-a]Pyrimidin-5-Yl)Piperidine-1-Carboxylate
CAS No.	877173-81-4
Molecular Formula	C16H19ClN4O2
Molecular Weight	334.80 g/mol
Synonyms	1-Boc-3-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine; tert-Butyl 3-(7-chloro-1H-pyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine; 877173-81-4; 3-(7-Chloro-1H-pyrazolo[1,5-a]pyrimidin-5-yl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; BOC-3-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-(7-chloropyrazolo[1,5-a]pyrimidin-5-yl)piperidine-1-carboxylate adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for pharmaceutical R&D. Products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.