Description

2-Chloro-n-(7-Hydroxy-5-Methyl-[1,2,4]Triazolo-[1,5-A]Pyrimidin-6-Yl)-Acetamide is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring heterocyclic scaffolds. It is primarily sought by R&D laboratories, process chemists, and manufacturers in the pharmaceutical and agrochemical sectors for synthesis and scale-up projects.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug molecules, especially those containing fused triazolopyrimidine cores.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that leverage its heterocyclic structure for biological activity.
• Chemical Synthesis Building Block: Serves as a versatile reagent for constructing more complex nitrogen-containing heterocycles in academic and industrial research.
• Biochemical Probe Development: Utilized in medicinal chemistry for creating tool compounds to study specific enzyme targets or biological pathways.
• Process Development & Optimization: Employed by process chemists for route scouting, optimization, and the development of scalable, cost-effective manufacturing processes for target molecules.

Basic Information

Product Name	2-Chloro-n-(7-Hydroxy-5-Methyl-[1,2,4]Triazolo-[1,5-A]Pyrimidin-6-Yl)-Acetamide
CAS No.	876717-51-0
Molecular Formula	C8H7ClN6O2
Molecular Weight	254.63 g/mol
Synonyms	2-Chloro-N-(7-hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)acetamide; 6-Acetamido-7-hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl Chloride; 2-Chloroacetamido-7-hydroxy-5-methyltriazolopyrimidine; 876717-51-0; Acetamide, 2-chloro-N-(7-hydroxy-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)-; 5-Methyl-7-hydroxy-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxamide, 2-chloro derivative
EINECS	Contact for details

Quality Control

Our production of 2-Chloro-n-(7-Hydroxy-5-Methyl-[1,2,4]Triazolo-[1,5-A]Pyrimidin-6-Yl)-Acetamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques like HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.