Description

4-Chloro-6-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key synthetic precursor in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its versatile halogen handles for further functionalization.
• Chemical Biology: Employed in the development of molecular probes and tool compounds for studying biological pathways.
• Agrochemical Research: Potential application as a building block for novel active ingredients in crop protection science.
• Academic Research: Utilized in methodological development and the synthesis of complex heterocyclic libraries.

Basic Information

Product Name	4-Chloro-6-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	876343-10-1
Molecular Formula	C6H3ClIN3
Molecular Weight	279.46 g/mol
Synonyms	4-Chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-iodo-; 4-Chloro-6-iodopyrrolo[2,3-d]pyrimidine; 4-Chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine; 876343-10-1; 4-Cl-6-I-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Iodo-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed in a dry, inert atmosphere to ensure long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.