Description

[1-(Pyrimidin-4-Yl)Piperidin-4-Yl]Methanamine is a high-purity, heterocyclic amine building block of significant interest in advanced organic synthesis. This compound, with CAS number 876144-84-2, is valued for its unique piperidine-pyrimidine hybrid structure, which serves as a critical pharmacophore in medicinal chemistry. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

This versatile chemical intermediate is designed for sophisticated synthesis applications, including:

• Pharmaceutical Intermediate: A key building block for the synthesis of small molecule drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection products.
• Chemical Biology: Employed as a molecular probe or linker in the study of biological pathways and target identification.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and custom synthesis houses to create complex, proprietary molecules for clients.
• Library Synthesis: Ideal for generating focused chemical libraries for high-throughput screening (HTS) in drug discovery campaigns.

Basic Information

Product Name	[1-(Pyrimidin-4-Yl)Piperidin-4-Yl]Methanamine
CAS No.	876144-84-2
Molecular Formula	C10H16N4
Molecular Weight	192.26 g/mol
Synonyms	4-(Aminomethyl)-1-(4-pyrimidinyl)piperidine; 1-(Pyrimidin-4-yl)piperidine-4-methanamine; 4-(Aminomethyl)-1-pyrimidin-4-ylpiperidine; 1-(4-Pyrimidinyl)-4-piperidinemethanamine; 4-Piperidinemethanamine, 1-(4-pyrimidinyl)-; (1-(Pyrimidin-4-yl)piperidin-4-yl)methanamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized to confirm identity and purity, with critical parameters controlled to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of a desiccant.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.