Description

Pyrimidine, 5-(Bromomethyl)-2-(2-Methylphenyl)- (9Ci) is a specialized brominated pyrimidine derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Chemical Biology: Employed in the synthesis of probes and tool compounds for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromomethyl group makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to introduce complex substituents.
• Library Synthesis: Used in combinatorial and parallel synthesis within medicinal chemistry to generate diverse compound libraries for screening.

Basic Information

Product Name	Pyrimidine, 5-(Bromomethyl)-2-(2-Methylphenyl)- (9Ci)
CAS No.	875777-66-5
Molecular Formula	C12H11BrN2
Molecular Weight	263.13 g/mol
Synonyms	5-(Bromomethyl)-2-(2-methylphenyl)pyrimidine; 2-(2-Methylphenyl)-5-(bromomethyl)pyrimidine; 5-(Bromomethyl)-2-o-tolylpyrimidine; 2-o-Tolyl-5-(bromomethyl)pyrimidine; (2-Methylphenyl)-5-(bromomethyl)pyrimidine; Pyrimidine, 5-(bromomethyl)-2-(2-methylphenyl)-; 875777-66-5; SCHEMBL21842227
EINECS	Contact for details

Quality Control

Our Pyrimidine, 5-(Bromomethyl)-2-(2-Methylphenyl)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.