Description

4-Bromo-2-Fluoro-6-(Trifluoromethyl)Aniline is a high-purity, multi-functional aromatic amine building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and trifluoromethyl substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D and production chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where it can modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the biological activity often imparted by the trifluoromethyl group.
• Material Science Precursor: Serves as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl and aniline derivatives.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where halogen and fluorine atoms influence color fastness and spectral properties.

Basic Information

Product Name	4-Bromo-2-Fluoro-6-(Trifluoromethyl)Aniline
CAS No.	875664-46-3
Molecular Formula	C7H4BrF4N
Molecular Weight	258.01 g/mol
Synonyms	2-Fluoro-4-bromo-6-(trifluoromethyl)aniline; 4-Bromo-2-fluoro-6-(trifluoromethyl)benzenamine; 1-Amino-4-bromo-2-fluoro-6-(trifluoromethyl)benzene; Benzenamine, 4-bromo-2-fluoro-6-(trifluoromethyl)-; 4-Bromo-2-fluoro-α,α,α-trifluoro-m-toluidine
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Fluoro-6-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.