Description

3-Bromo-5-Fluoro-4-Methoxyaniline is a high-purity, multi-functional aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging its halogenated aniline core.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing advanced azo dyes and high-performance pigments.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research and diagnostic applications.

Basic Information

Product Name	3-Bromo-5-Fluoro-4-Methoxyaniline
CAS No.	875664-44-1
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	4-Amino-2-bromo-6-fluoroanisole; 2-Bromo-6-fluoro-4-methoxyaniline; 3-Bromo-5-fluoro-p-anisidine; Benzenamine, 3-bromo-5-fluoro-4-methoxy-; 4-Methoxy-3-bromo-5-fluoroaniline; 875664-44-1; 3-Br-5-F-4-MeO-aniline
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Fluoro-4-Methoxyaniline is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, GC, NMR, and elemental analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.