Description

2-Iodo-5-(Trifluoromethyl)Benzaldehyde is a versatile and high-value halogenated aromatic aldehyde building block. Its unique structure, featuring both an iodine atom and a trifluoromethyl group, makes it a critical intermediate for synthesizing complex molecules in advanced research and development. This compound is primarily sought after by pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials. Its reactivity allows for selective cross-coupling and further functionalization, enabling the development of targeted compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), improving performance and durability.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings, facilitating complex molecule assembly.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis and other catalytic processes.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Iodo-5-(Trifluoromethyl)Benzaldehyde
CAS No.	875446-23-4
Molecular Formula	C8H4F3IO
Molecular Weight	300.02 g/mol
Synonyms	2-Iodo-α,α,α-trifluoro-m-tolualdehyde; 5-(Trifluoromethyl)-2-iodobenzaldehyde; m-Trifluoromethyl-2-iodobenzaldehyde; 2-Iodo-5-trifluoromethylbenzaldehyde; 2-Iodo-α,α,α-trifluoro-3-formyltoluene; Benzaldehyde, 2-iodo-5-(trifluoromethyl)-; 3-Iodo-6-(trifluoromethyl)benzaldehyde (alternative numbering)
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced material research, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.