Description

4-Chloro-6-Phenyl-5H-Pyrrolo[3,2-D]Pyrimidine is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is critical for medicinal chemistry research and the development of novel therapeutic agents, particularly kinase inhibitors. It is primarily sought after by R&D laboratories, custom synthesis providers, and pharmaceutical companies engaged in drug discovery programs targeting oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of targeted small-molecule drugs, especially protein kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new chemical entities.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and validate novel drug targets.
• Custom Synthesis & Contract Manufacturing: A key starting material for the cGMP or non-GMP production of active pharmaceutical ingredients (APIs) and advanced intermediates.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	4-Chloro-6-Phenyl-5H-Pyrrolo[3,2-D]Pyrimidine
CAS No.	875340-50-4
Molecular Formula	C₁₂H₈ClN₃
Molecular Weight	229.66 g/mol
Synonyms	4-Chloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidine; 6-Phenyl-4-chloro-5H-pyrrolo[3,2-d]pyrimidine; 4-Chloro-6-phenyl-7H-pyrrolo[3,2-d]pyrimidine; 875340-50-4; Pyrrolo[3,2-d]pyrimidine, 4-chloro-6-phenyl-; 4-Chloro-6-phenyl-pyrrolo[3,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Phenyl-5H-Pyrrolo[3,2-D]Pyrimidine is produced under strict quality management protocols. We offer material suitable for research and development use, with typical purity levels exceeding 95% (HPLC). Each batch is accompanied by comprehensive analytical data, including HPLC chromatograms and ¹H NMR spectra. Certificates of Analysis (COA) are available upon request to ensure traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Melting Point	Contact for details
Water Content (KF)	< 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.