Description

Methyl 2-[4-(Aminomethyl)Piperidin-1-Yl]Pyrimidine-5-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant intermediate with the CAS registry number 875318-56-2. This compound is valued for its role as a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry. It is essential for research institutions and manufacturers engaged in the development of novel drug candidates, where consistent quality and reliable supply are paramount.

Application

This specialized chemical intermediate serves as a key precursor in several advanced chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Active Pharmaceutical Ingredient (API) Development: Used in the research and scale-up phases for creating new therapeutic molecules.
• Chemical Synthesis Research: Employed in academic and industrial R&D for constructing complex piperidine-pyrimidine based molecular architectures.
• Process Chemistry & Route Scouting: Utilized by process chemists to develop and optimize scalable synthetic routes for target molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	Methyl 2-[4-(Aminomethyl)Piperidin-1-Yl]Pyrimidine-5-Carboxylate Hydrochloride
CAS No.	875318-56-2
Molecular Formula	C12H19ClN4O2
Molecular Weight	286.76 g/mol
Synonyms	Methyl 2-(4-(aminomethyl)piperidin-1-yl)pyrimidine-5-carboxylate hydrochloride; 2-[4-(Aminomethyl)-1-piperidinyl]-5-pyrimidinecarboxylic acid methyl ester hydrochloride; Methyl 2-(4-(aminomethyl)piperidin-1-yl)pyrimidine-5-carboxylate HCl; 1-Piperidinecarboxylic acid, 4-(aminomethyl)-, methyl ester, hydrochloride (9CI); 875318-56-2; Aminomethylpiperidine pyrimidine carboxylate ester hydrochloride
EINECS	Contact for details

Quality Control

Our production of Methyl 2-[4-(Aminomethyl)Piperidin-1-Yl]Pyrimidine-5-Carboxylate Hydrochloride adheres to stringent quality management protocols. Each batch is manufactured under controlled conditions and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, residual solvents, and appearance are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.