Description

n-Boc-L-Valinyl-L-Leucinyl Anilide is a high-purity, protected dipeptide building block designed for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring precise control over peptide chain assembly, particularly in the development of complex bioactive molecules. It is primarily utilized in pharmaceutical R&D for the synthesis of peptide-based drug candidates and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of complex therapeutic peptides.
• Peptide Drug Discovery: Used in research laboratories for constructing peptide libraries and screening for new drug leads.
• Bioconjugation: Serves as a precursor for creating peptide conjugates with other molecules like dyes, polymers, or proteins.
• Chemical Biology Probes: Employed in the synthesis of labeled peptides for studying biological mechanisms and protein interactions.
• Academic & Institutional Research: Fundamental reagent for studies in organic chemistry, medicinal chemistry, and peptide science.
• Custom Peptide Synthesis: Essential for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides for clients.

Basic Information

Product Name	n-Boc-L-Valinyl-L-Leucinyl Anilide
CAS No.	874899-05-5
Molecular Formula	C22H35N3O5
Molecular Weight	421.53 g/mol
Synonyms	Boc-Val-Leu-NH-Ph; N-(tert-Butoxycarbonyl)-L-valyl-L-leucyl anilide; tert-Butyl (2S)-2-[[(2S)-2-[(phenylamino)carbonyl]amino]-4-methylpentanoyl]amino]-3-methylbutanoate; Boc-L-Val-L-Leu-anilide; N-Boc-L-Val-L-Leu-anilide; L-Leucine, N-[N-[(1,1-dimethylethoxy)carbonyl]-L-valyl]-, anilide; (S)-2-((S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutanamido)-4-methyl-N-phenylpentanamide
EINECS	Contact for details

Quality Control

Our n-Boc-L-Valinyl-L-Leucinyl Anilide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant pharmaceutical development guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Specific Rotation	-XX° to -YY° (c=1, in Methanol)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.