Description

4-(3-Chlorophenyl)-5-Methylpyrimidin-2-Amine is a high-purity pyrimidine derivative, a crucial heterocyclic building block in advanced organic synthesis. This compound matters because it serves as a key intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables targeted molecular design. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization to create libraries of compounds for high-throughput screening.
• Material Science: Potential intermediate in the synthesis of organic electronic materials or metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential for fundamental research in medicinal chemistry and heterocyclic compound development.

Basic Information

Product Name	4-(3-Chlorophenyl)-5-Methylpyrimidin-2-Amine
CAS No.	874814-28-5
Molecular Formula	C11H10ClN3
Molecular Weight	219.67 g/mol
Synonyms	2-Amino-4-(3-chlorophenyl)-5-methylpyrimidine; 5-Methyl-4-(3-chlorophenyl)pyrimidin-2-amine; 4-(3-Chlorophenyl)-5-methyl-2-pyrimidinamine; 4-(3-Chlorophenyl)-5-methylpyrimidin-2-ylamine; 874814-28-5; 4-(3-Chloro-phenyl)-5-methyl-pyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Our 4-(3-Chlorophenyl)-5-Methylpyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.