Description

4-([4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy)Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrimidine-oxygen-benzaldehyde scaffold. This compound matters for its critical role as a versatile building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. Pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers need this precise intermediate to develop next-generation small-molecule therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted kinase inhibitors and other small-molecule drugs.
• Agrochemical Research: Used in developing novel fungicides and herbicides with enhanced activity and selectivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers with specific electronic or surface properties.
• Organic Synthesis: A versatile building block for constructing complex heterocyclic compounds in medicinal chemistry.
• Chemical Biology: Employed in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Product Name	4-([4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy)Benzaldehyde
CAS No.	874782-05-5
Molecular Formula	C₁₂H₇F₃N₂O₂
Molecular Weight	268.19 g/mol
Synonyms	4-[(4-Trifluoromethyl-2-pyrimidinyl)oxy]benzaldehyde; 4-(4-Trifluoromethylpyrimidin-2-yloxy)benzaldehyde; Benzaldehyde, 4-[[4-(trifluoromethyl)-2-pyrimidinyl]oxy]-; 2-(4-Formylphenoxy)-4-(trifluoromethyl)pyrimidine; 4-((4-(Trifluoromethyl)pyrimidin-2-yl)oxy)benzaldehyde
EINECS	Contact for details

Quality Control

Our 4-([4-(Trifluoromethyl)Pyrimidin-2-Yl]Oxy)Benzaldehyde is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.