Description

4-(2,4-Difluorophenyl)Pyrimidin-2-Amine is a high-purity, fluorinated pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological or material properties. This compound is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor programs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and pesticides that leverage its fluorinated aromatic structure.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a difluorophenyl-pyrimidine motif.
• Academic & Institutional Research: Used in university and institutional labs for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	4-(2,4-Difluorophenyl)Pyrimidin-2-Amine
CAS No.	874779-68-7
Molecular Formula	C10H7F2N3
Molecular Weight	207.18 g/mol
Synonyms	2-Amino-4-(2,4-difluorophenyl)pyrimidine; 4-(2,4-Difluorophenyl)-2-pyrimidinamine; 2-Pyrimidinamine, 4-(2,4-difluorophenyl)-; 874779-68-7; 4-(2,4-Difluorophenyl)-2-aminopyrimidine; 4-(2,4-Difluorophenyl)pyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Our 4-(2,4-Difluorophenyl)Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.