Description

4-(2-Chlorophenyl)Pyrimidin-2-Amine is a high-purity, specialized pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral agent development.
• Agrochemical Research: Used in the discovery and production of new-generation herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or functional component in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology Probe: Employed in biochemical research as a scaffold for developing enzyme inhibitors and molecular probes to study biological pathways.
• Custom Synthesis Building Block: Provides a chlorophenyl-pyrimidine core for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	4-(2-Chlorophenyl)Pyrimidin-2-Amine
CAS No.	874766-80-0
Molecular Formula	C10H8ClN3
Molecular Weight	205.64 g/mol
Synonyms	2-Amino-4-(2-chlorophenyl)pyrimidine; 4-(2-Chlorophenyl)-2-pyrimidinamine; 2-Pyrimidinamine, 4-(2-chlorophenyl)-; 4-(o-Chlorophenyl)pyrimidin-2-amine; 2-Chloro-4-aminopyrimidine phenyl derivative; (2-Chlorophenyl)pyrimidin-2-amine; CAS 874766-80-0
EINECS	Contact for details

Quality Control

Every batch of 4-(2-Chlorophenyl)Pyrimidin-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.