Description

4-[(Methylamino)Carbonyl]Benzenesulfonyl Chloride (Saltdata: Free) is a high-purity sulfonyl chloride derivative, a critical building block in advanced organic synthesis. Its primary value lies in its dual reactive sites, enabling its use as a key intermediate for constructing complex molecules with specific sulfonamide and amide functionalities. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting enzyme inhibition via sulfonamide groups.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the benzenesulfonyl moiety is required for bioactivity.
• Peptide Modification & Bioconjugation: Serves as a reactive handle for modifying peptides, proteins, or other biomolecules to introduce sulfonamide linkages.
• Material Science Research: Employed in the creation of specialty polymers, dyes, and functional materials that incorporate sulfonyl chloride chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring high-purity, specialized aromatic sulfonyl chlorides.

Basic Information

Product Name	4-[(Methylamino)Carbonyl]Benzenesulfonyl Chloride (Saltdata: Free)
CAS No.	874622-79-4
Molecular Formula	C9H8ClNO3S
Molecular Weight	245.68 g/mol
Synonyms	4-(Methylcarbamoyl)benzenesulfonyl chloride; N-Methyl-4-sulfamoylbenzamide chloride; p-(N-Methylaminocarbonyl)benzenesulfonyl chloride; 4-(Methylaminocarbonyl)benzenesulfonyl chloride; Methyl 4-(chlorosulfonyl)benzamide; 874622-79-4; Benzenesulfonyl chloride, 4-[(methylamino)carbonyl]-
EINECS	Contact for details

Quality Control

Our 4-[(Methylamino)Carbonyl]Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.