Description

5-Chloro-n-(2,4-Dimethoxyphenyl)-2-(Methylsulfonyl)Pyrimidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate with a distinct pyrimidine carboxamide core structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), enabling research and development in targeted therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers engaged in developing new small-molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology and antiviral therapeutic areas.
• Agrochemical Research: Serves as a core scaffold for developing novel herbicides, fungicides, or insecticides with specific modes of action.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition or modulate biological pathways due to its sulfonyl and carboxamide functional groups.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value compounds for various industrial applications.
• Material Science Research: Potential building block for creating novel organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Chloro-n-(2,4-Dimethoxyphenyl)-2-(Methylsulfonyl)Pyrimidine-4-Carboxamide
CAS No.	874355-33-6
Molecular Formula	C14H14ClN3O5S
Molecular Weight	371.80 g/mol
Synonyms	5-Chloro-N-(2,4-dimethoxyphenyl)-2-(methylsulfonyl)pyrimidine-4-carboxamide; 2-(Methylsulfonyl)-5-chloro-N-(2,4-dimethoxyphenyl)pyrimidine-4-carboxamide; 874355-33-6; 5-Chloro-2-methanesulfonyl-N-(2,4-dimethoxyphenyl)pyrimidine-4-carboxamide; Pyrimidine-4-carboxamide, 5-chloro-N-(2,4-dimethoxyphenyl)-2-(methylsulfonyl)-; 5-Chloro-N-(2,4-dimethoxyphenyl)-2-(methylsulfonyl)-4-pyrimidinecarboxamide
EINECS	Contact for details

Quality Control

Our 5-Chloro-n-(2,4-Dimethoxyphenyl)-2-(Methylsulfonyl)Pyrimidine-4-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full batch traceability are provided to guarantee consistent quality and supply reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.