Description

5-Chloro-2-[(4-Fluorobenzyl)Sulfanyl]-n-Phenylpyrimidine-4-Carboxamide is a high-purity, synthetically derived pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacological intermediate and a versatile chemical building block for research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other targeted therapeutic areas.
• Chemical Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization processes.
• Research & Development: Serves as a standard or reference compound in academic and industrial laboratories for method development and biochemical screening.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for agrochemical and material science applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP guidelines.

Basic Information

Product Name	5-Chloro-2-[(4-Fluorobenzyl)Sulfanyl]-n-Phenylpyrimidine-4-Carboxamide
CAS No.	874137-54-9
Molecular Formula	C18H13ClFN3OS
Molecular Weight	373.83 g/mol
Synonyms	5-Chloro-2-[(4-fluorobenzyl)thio]-N-phenyl-4-pyrimidinecarboxamide; 5-Chloro-2-((4-fluorobenzyl)thio)-N-phenylpyrimidine-4-carboxamide; 874137-54-9; 5-Chloro-2-[(4-fluorobenzyl)sulfanyl]-N-phenyl-4-pyrimidinecarboxamide; 5-Chloro-2-[(4-fluorobenzyl)sulfanyl]-N-phenylpyrimidine-4-carboxamide; 5-Chloro-2-[(4-fluorobenzyl)thio]-N-phenyl-4-pyrimidinecarboxamide; 5-Chloro-2-((4-fluorobenzyl)thio)-N-phenyl-4-pyrimidinecarboxamide
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-[(4-Fluorobenzyl)Sulfanyl]-n-Phenylpyrimidine-4-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.