Description

4-Chloro-5-Iodo-1H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is a high-purity, heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the life sciences sector for the creation of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization campaigns.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Agrochemical Development: Acts as a building block for novel active ingredients in crop protection research.
• Academic Research: Utilized in universities and research institutes for methodological development in heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines.

Basic Information

Product Name	4-Chloro-5-Iodo-1H-Pyrrolo[2,3-D]Pyrimidin-2-Amine
CAS No.	873792-88-2
Molecular Formula	C6H4ClIN4
Molecular Weight	294.48 g/mol
Synonyms	4-Chloro-5-iodo-1H-pyrrolo[2,3-d]pyrimidin-2-amine; 4-Chloro-5-iodo-2-amino-7H-pyrrolo[2,3-d]pyrimidine; 2-Amino-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine; 4-Chloro-5-iodo-1H-pyrrolo[2,3-d]pyrimidin-2-ylamine; 873792-88-2; 4-Chloro-5-iodo-pyrrolo[2,3-d]pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Iodo-1H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.