Description

5-Bromo-4-Chloro-1H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is a high-purity heterocyclic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the creation of novel kinase inhibitors and other targeted therapeutic agents. It is primarily sought after by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the synthesis of complex molecules for oncology and other disease areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule kinase inhibitors and other targeted cancer therapies.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies for novel drug candidates.
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for clinical trial materials.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and bio-active compound libraries.

Basic Information

Product Name	5-Bromo-4-Chloro-1H-Pyrrolo[2,3-D]Pyrimidin-2-Amine
CAS No.	873792-87-1
Molecular Formula	C6H4BrClN4
Molecular Weight	247.48 g/mol
Synonyms	5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine; 4-Chloro-5-bromo-1H-pyrrolo[2,3-d]pyrimidin-2-amine; 2-Amino-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine; 5-Bromo-4-chloro-2-amino-7H-pyrrolo[2,3-d]pyrimidine; 873792-87-1; 5-Br-4-Cl-1H-pyrrolo[2,3-d]pyrimidin-2-amine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloro-1H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.