Description

Benzenecarboximidamide, 4-[3-[1-[3-[4-(Aminoiminomethyl)Phenoxy]Propyl]-4-Piperidinyl]Propoxy]-, Hydrochloride, Hydrate (1:3:5) is a complex, high-purity chemical building block of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key intermediate in the synthesis of novel therapeutic agents, particularly those targeting specific receptor pathways. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology industries engaged in creating new drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or cardiovascular targets.
• Biochemical Research: Used as a reference standard or a tool compound in pharmacological studies to investigate receptor binding and enzyme inhibition mechanisms.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale, requiring high chemical purity and consistency.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials under GMP conditions.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead drug molecules.

Basic Information

Product Name	Benzenecarboximidamide, 4-[3-[1-[3-[4-(Aminoiminomethyl)Phenoxy]Propyl]-4-Piperidinyl]Propoxy]-, Hydrochloride, Hydrate (1:3:5)
CAS No.	873546-38-4
Molecular Formula	C25H37ClN4O2 • 5H2O
Molecular Weight	Contact for details
Synonyms	4-[3-[1-[3-[4-(Aminoiminomethyl)Phenoxy]Propyl]-4-Piperidinyl]Propoxy]benzenecarboximidamide Hydrochloride Hydrate; 4-[3-[1-[3-[4-(Aminoiminomethyl)Phenoxy]Propyl]piperidin-4-yl]propoxy]benzamidine Hydrochloride Hydrate; 873546-38-4; UNII-8K3F6B4W2M; 8K3F6B6W2M; Benzamidine derivative piperidine compound; 4-(3-(1-(3-(4-(Aminoiminomethyl)phenoxy)propyl)piperidin-4-yl)propoxy)benzamidine hydrochloride pentahydrate
EINECS	Contact for details

Quality Control

Our Benzenecarboximidamide derivative is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for sensitive R&D and scale-up applications. Each lot undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and water content. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	Consistent with hydrate form
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.