Description

2-Morpholin-4-Yl-4-(Trifluoromethyl)-Pyrimidine-5-Carboxylic Acid is a high-value, multifunctional heterocyclic building block featuring a pyrimidine core substituted with a morpholine ring and a trifluoromethyl group. This compound matters as a critical intermediate in modern pharmaceutical and agrochemical research, where its unique structure enables the synthesis of novel active ingredients with enhanced properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrimidine and trifluoromethyl motifs.
• Chemical Biology Probe Development: Serves as a scaffold for creating tool compounds to study biological pathways and protein function.
• Material Science Precursor: Potential building block for advanced organic electronic materials or metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules at various scales.

Basic Information

Product Name	2-Morpholin-4-Yl-4-(Trifluoromethyl)-Pyrimidine-5-Carboxylic Acid
CAS No.	873450-23-8
Molecular Formula	C10H10F3N3O3
Molecular Weight	277.20 g/mol
Synonyms	4-(Trifluoromethyl)-2-(morpholin-4-yl)pyrimidine-5-carboxylic acid; 2-Morpholino-4-(trifluoromethyl)pyrimidine-5-carboxylic acid; 873450-23-8; 4-(Trifluoromethyl)-2-morpholin-4-yl-5-pyrimidinecarboxylic acid; 5-Pyrimidinecarboxylic acid, 4-(trifluoromethyl)-2-(4-morpholinyl)-; 2-(Morpholin-4-yl)-4-(trifluoromethyl)pyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Morpholin-4-Yl-4-(Trifluoromethyl)-Pyrimidine-5-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.