Description

6-Methyl-2-Morpholin-4-Yl-Pyrimidine-4-Carboxylic Acid is a high-purity, synthetically valuable heterocyclic building block. This compound is a key intermediate in the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs. It is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of targeted kinase inhibitors for oncology and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate in the scale-up and optimization of API manufacturing routes.
• Agrochemical Synthesis: Employed in the research and development of novel crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects.

Basic Information

Product Name	6-Methyl-2-Morpholin-4-Yl-Pyrimidine-4-Carboxylic Acid
CAS No.	873450-14-7
Molecular Formula	C10H13N3O3
Molecular Weight	223.23 g/mol
Synonyms	4-Pyrimidinecarboxylic acid, 6-methyl-2-(4-morpholinyl)-; 6-Methyl-2-(morpholin-4-yl)pyrimidine-4-carboxylic acid; 2-Morpholin-4-yl-6-methylpyrimidine-4-carboxylic acid; 6-Methyl-2-(4-morpholinyl)-4-pyrimidinecarboxylic acid; 873450-14-7; 6-Methyl-2-morpholin-4-yl-pyrimidine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Methyl-2-Morpholin-4-Yl-Pyrimidine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring GMP-grade intermediates and materials for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.