Description

4-Chloro-6-Methylamino-Pyrimidine-5-Carbonitrile is a high-purity pyrimidine derivative building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, enabling the construction of complex heterocyclic structures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors, antiviral agents, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a versatile precursor for creating specialized dyes, pigments, and functional materials.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Useful in the development of molecular probes for studying enzymatic activity and biological pathways.

Basic Information

Product Name	4-Chloro-6-Methylamino-Pyrimidine-5-Carbonitrile
CAS No.	872890-15-8
Molecular Formula	C7H7ClN4
Molecular Weight	182.61 g/mol
Synonyms	4-Chloro-6-(methylamino)pyrimidine-5-carbonitrile; 5-Cyano-4-chloro-6-methylaminopyrimidine; 6-Methylamino-4-chloropyrimidine-5-carbonitrile; 872890-15-8; 4-Chloro-6-methylamino-5-cyanopyrimidine; 4-Chloro-6-(N-methylamino)pyrimidine-5-carbonitrile; 5-Pyrimidinecarbonitrile, 4-chloro-6-(methylamino)-
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-Methylamino-Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The material is moisture-sensitive; ensure containers are sealed tightly after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.