Description

Acetic Acid, 2-[(2S)-2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-3-Phenylpropoxy]- is a specialized, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture, particularly in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules. It serves as a key intermediate for pharmaceutical R&D, peptide synthesis, and fine chemical production, where its defined stereochemistry and protected functional groups are essential.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis, particularly where the Fmoc-protected amino acid derivative is required.
• Organic Synthesis & Research: Serves as a key chiral synthon in academic and industrial research for constructing complex organic molecules with specific stereocenters.
• Protecting Group Chemistry: Utilized in methodologies where the 9H-fluoren-9-ylmethoxycarbonyl (Fmoc) group is employed for temporary amine protection.
• Fine Chemical Production: An intermediate in the manufacture of high-value specialty chemicals, agrochemicals, and advanced materials.
• Bioconjugation: Potential use in the development of antibody-drug conjugates (ADCs) and other bioconjugation strategies due to its reactive handle.

Basic Information

Product Name	Acetic Acid, 2-[(2S)-2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-3-Phenylpropoxy]-
CAS No.	872721-12-5
Molecular Formula	C26H25NO5
Molecular Weight	431.48 g/mol
Synonyms	Fmoc-L-Phenylalaninol Acetate; (2S)-2-[[(9H-Fluoren-9-Ylmethoxy)carbonyl]amino]-3-phenylpropyl acetate; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-phenylalaninol acetate; Nα-Fmoc-L-phenylalaninol acetate; Fmoc-Phe-ol acetate; Fmoc-L-Phenylalaninol O-acetate; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-phenylpropyl acetate
EINECS	Contact for details

Quality Control

Our Acetic Acid, 2-[(2S)-2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-3-Phenylpropoxy]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, chemical purity (by HPLC), and identity confirmation. We adhere to cGMP guidelines where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (S-isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.