Description

2-Iodo-4-Methyl-5-(Trifluoromethyl)Benzenamine is a high-value, multi-functional halogenated aniline derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery for CNS, oncology, and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging the trifluoromethyl group for enhanced bioactivity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and cross-coupling reactions (e.g., Buchwald-Hartwig amination).
• Material Science Research: Intermediate in the synthesis of organic electronic materials, such as charge-transport molecules or fluorinated polymers.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	2-Iodo-4-Methyl-5-(Trifluoromethyl)Benzenamine
CAS No.	872624-68-5
Molecular Formula	C8H7F3IN
Molecular Weight	301.05 g/mol
Synonyms	2-Iodo-4-methyl-5-(trifluoromethyl)aniline; 5-Amino-2-iodo-α,α,α-trifluoro-p-xylene; 2-Iodo-α,α,α-trifluoro-4-methyl-5-aminotoluene; 2-Iodo-4-methyl-5-trifluoromethylaniline; 5-(Trifluoromethyl)-2-iodo-4-methylbenzenamine; Benzenamine, 2-iodo-4-methyl-5-(trifluoromethyl)-; 872624-68-5
EINECS	Contact for details

Quality Control

Our 2-Iodo-4-Methyl-5-(Trifluoromethyl)Benzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.