Description

4-Pyrimidinamine, 2-Fluoro-5-Nitro- is a high-purity fluorinated and nitrated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which introduces both fluorine and nitro functional groups to the pyrimidine core, enabling precise modifications in target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, leveraging the bioactivity of the fluoronitropyrimidine scaffold.
• Chemical Research: Serves as a versatile precursor in academic and industrial laboratories for heterocyclic chemistry and structure-activity relationship (SAR) studies.
• Material Science: Potential building block for the synthesis of specialty polymers, ligands for catalysis, and advanced organic electronic materials.

Basic Information

Product Name	4-Pyrimidinamine, 2-Fluoro-5-Nitro-
CAS No.	872530-03-5
Molecular Formula	C4H3FN4O2
Molecular Weight	158.09 g/mol
Synonyms	2-Fluoro-5-nitropyrimidin-4-amine; 5-Nitro-2-fluoropyrimidin-4-amine; 4-Amino-2-fluoro-5-nitropyrimidine; 2-Fluoro-5-nitro-4-pyrimidinamine; 872530-03-5; 2-Fluoro-5-nitropyrimidine-4-amine; 4-Pyrimidinamine, 2-fluoro-5-nitro-
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-5-nitropyrimidin-4-amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing lot-specific results are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.