Description

Benzenamine, 3,5-Difluoro-n-Methyl-2-Nitro- is a high-purity, specialized aromatic amine derivative, identified by CAS No. 872367-64-1. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the development of novel molecular structures. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of complex, fluorinated target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the difluoro and nitro substituents contribute to biological activity and metabolic stability.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport materials or host materials in OLED displays and lighting, leveraging its aromatic and fluorinated structure.
• Liquid Crystal & Polymer Research: Employed in the development of specialty monomers for high-performance polymers and liquid crystal compounds for electronic applications.
• Cross-Coupling Reactions: Serves as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) to create complex biaryl amines.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized, high-value fluorinated dyes and pigments for niche applications.

Basic Information

Product Name	Benzenamine, 3,5-Difluoro-n-Methyl-2-Nitro-
CAS No.	872367-64-1
Molecular Formula	C7H6F2N2O2
Molecular Weight	188.13 g/mol
Synonyms	3,5-Difluoro-N-methyl-2-nitroaniline; N-Methyl-3,5-difluoro-2-nitroaniline; 2-Nitro-3,5-difluoro-N-methylaniline; 3,5-Difluoro-2-nitro-N-methylbenzenamine; 1,3-Difluoro-5-(methylamino)-2-nitrobenzene; N-Methyl-2-nitro-3,5-difluoroaniline; 872367-64-1 (CAS Registry)
EINECS	Contact for details

Quality Control

Our Benzenamine, 3,5-Difluoro-n-Methyl-2-Nitro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and scale-up with custom purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (HPLC)	≥ 99.0% (High Purity Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.