Description

2,6-Dimethyl-4'-(Trifluoromethyl)-1,1'-Biphenyl-4-Ol is a high-value biphenyl derivative characterized by its phenolic hydroxyl group and trifluoromethyl substituent, which imparts unique electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis, enabling the development of novel active ingredients. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecules with enhanced bioactivity and stability.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated compounds for improved metabolic stability and membrane permeability.
• Agrochemical Active Ingredient Precursor: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances efficacy.
• Liquid Crystal & OLED Material Synthesis: Serves as a core structure or side-chain modifier in the production of advanced electronic display materials and organic light-emitting diodes (OLEDs).
• Ligand for Catalysis: Can be utilized to develop specialized ligands for transition metal catalysts used in cross-coupling and other asymmetric synthesis reactions.
• Polymer & Resin Modifier: Incorporated into polymer backbones to alter physical properties such as thermal stability, solubility, and refractive index for high-performance materials.
• Research & Development: An essential tool for medicinal and process chemists in academia and industry for exploring new chemical spaces and reaction pathways.

Basic Information

Product Name	2,6-Dimethyl-4'-(Trifluoromethyl)-1,1'-Biphenyl-4-Ol
CAS No.	872258-58-7
Molecular Formula	C15H13F3O
Molecular Weight	266.26 g/mol
Synonyms	4'-(Trifluoromethyl)-2,6-dimethyl-[1,1'-biphenyl]-4-ol; [1,1'-Biphenyl]-4-ol, 4'-(trifluoromethyl)-2,6-dimethyl-; 2,6-Dimethyl-4'-(trifluoromethyl)biphenyl-4-ol; 4-Hydroxy-2,6-dimethyl-4'-(trifluoromethyl)biphenyl; 2,6-Dimethyl-4'-(trifluoromethyl)-1,1'-biphenyl-4-ol; Biphenyl-4-ol, 2,6-dimethyl-4'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-4'-(Trifluoromethyl)-1,1'-Biphenyl-4-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to protect the contents from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.