Description

n-[3-Cyano-1-(3-Methoxypropyl)-10-Methyl-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-3-Methoxybenzamide CAS NO 872118-28-0 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical studies.
• Chemical Biology Probes: Utilized in the development of specialized probes for studying enzyme function and cellular signaling pathways.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	n-[3-Cyano-1-(3-Methoxypropyl)-10-Methyl-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-3-Methoxybenzamide
CAS No.	872118-28-0
Molecular Formula	C25H23N5O4
Molecular Weight	457.48 g/mol
Synonyms	3-Methoxy-N-[3-cyano-1-(3-methoxypropyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene]benzamide; UNII-3R9Q8V8Q6F; 872118-28-0; 3-Methoxy-N-(3-cyano-1-(3-methoxypropyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene)benzamide; Benzamide, 3-methoxy-N-[3-cyano-1-(3-methoxypropyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene]-; 3R9Q8V8Q6F; BDBM50389335; ZINC000006928008.
EINECS	Contact for details

Quality Control

Our n-[3-Cyano-1-(3-Methoxypropyl)-10-Methyl-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-3-Methoxybenzamide is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment. We support compliance with cGMP and ISO standards for pharmaceutical intermediates, and specifications can be aligned with client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.