Description

Polybia-Mp1 Trifluoroacetate Salt is a synthetic peptide derivative of a natural mastoparan wasp venom component, offered as a high-purity trifluoroacetate salt. This compound is valued for its potent, selective biological activity, making it a critical research tool for studying ion channel function, antimicrobial mechanisms, and cell membrane interactions. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on peptide-based drug discovery and basic biochemical research.

Application

• Biomedical Research: Investigation of mast cell degranulation, G-protein signaling pathways, and antimicrobial peptide (AMP) mechanisms.
• Ion Channel Studies: Used as a research tool to modulate and study the activity of various cation channels in cellular models.
• Drug Discovery: Serves as a lead compound or structural template for developing novel peptide therapeutics with antimicrobial or immunomodulatory properties.
• Cell Biology: Study of peptide-induced pore formation in lipid bilayers and membrane permeability assays.
• Biochemical Reagent: Utilized in enzymatic studies and as a standard in analytical method development for peptide quantification.

Basic Information

Product Name	Polybia-Mp1 Trifluoroacetate Salt
CAS No.	872043-01-1
Molecular Formula	C81H124N24O19 • C2HF3O2
Molecular Weight	~1780.0 g/mol (Free base: 1685.0)
Synonyms	Polybia-MP1 TFA salt; Mastoparan MP-1; Polybia-MP1 acetate (trifluoro); INWARFIAALIKKI-NH2 TFA; Polybia-MP I; Antimicrobial peptide Polybia-MP1; Polybia-MP-1 trifluoroacetate; Polybia mastoparan-1
EINECS	Contact for details

Quality Control

Our Polybia-Mp1 Trifluoroacetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and residual solvent levels is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	Reported on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.