Description

3-Cyclopropyl-1-(2-Fluoro-4-Iodophenyl)-6,8-Dimethyl-2,4,7-Trioxo-1,2,3,4,7,8-Hexahydropyrido[2,3-D]Pyrimidin-5-Yl 4-Methylbenzenesulfonate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a key building block for novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers targeting oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drug candidates, particularly in oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes for new therapeutic targets.
• API Synthesis: Serves as a crucial building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for cutting-edge research in heterocyclic and pharmaceutical chemistry.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	3-Cyclopropyl-1-(2-Fluoro-4-Iodophenyl)-6,8-Dimethyl-2,4,7-Trioxo-1,2,3,4,7,8-Hexahydropyrido[2,3-D]Pyrimidin-5-Yl 4-Methylbenzenesulfonate
CAS No.	871700-32-2
Molecular Formula	C25H21FIN3O6S
Molecular Weight	637.41 g/mol
Synonyms	3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-yl tosylate; 3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydro-5H-pyrido[2,3-d]pyrimidin-5-yl 4-methylbenzenesulfonate; 871700-32-2; Pyrido[2,3-d]pyrimidine tosylate derivative; Tosylate ester of hexahydropyridopyrimidine
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-1-(2-Fluoro-4-Iodophenyl)-6,8-Dimethyl-2,4,7-Trioxo-1,2,3,4,7,8-Hexahydropyrido[2,3-D]Pyrimidin-5-Yl 4-Methylbenzenesulfonate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.