Description

1-(2,4-Dichloropyrimidin-5-Yl)Ethanone is a high-purity, versatile pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized dichloropyrimidine core, which enables selective and efficient derivatization for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for synthesizing functionalized heterocyclic compounds used in organic electronic materials and ligands.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract research and manufacturing organizations (CROs/CMOs) to produce bespoke compounds for clients.

Basic Information

Product Name	1-(2,4-Dichloropyrimidin-5-Yl)Ethanone
CAS No.	871254-62-5
Molecular Formula	C6H4Cl2N2O
Molecular Weight	191.01 g/mol
Synonyms	5-Acetyl-2,4-dichloropyrimidine; 2,4-Dichloro-5-acetylpyrimidine; Ethanone, 1-(2,4-dichloro-5-pyrimidinyl)-; 1-(2,4-Dichloro-5-pyrimidinyl)ethanone; 2,4-Dichloropyrimidin-5-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(2,4-Dichloropyrimidin-5-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.