Description

2-(4-Trifluoromethylphenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester is a high-value fluorinated pyrimidine derivative, a key synthetic intermediate prized for its structural complexity and functional versatility. This compound is critical for research and development in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the pyrimidine core.
• Material Science: Serves as a precursor for advanced organic electronic materials, including OLEDs and semiconductors, due to its conjugated system and fluorine content.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization in medicinal and combinatorial chemistry for library generation.
• Academic & Industrial R&D: Employed in research laboratories for studying structure-activity relationships (SAR) and developing new synthetic methodologies.

Basic Information

Product Name	2-(4-Trifluoromethylphenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	871251-66-0
Molecular Formula	C13H9F3N2O2
Molecular Weight	282.22 g/mol
Synonyms	Methyl 2-[4-(trifluoromethyl)phenyl]pyrimidine-5-carboxylate; 2-(4-(Trifluoromethyl)phenyl)pyrimidine-5-carboxylic acid methyl ester; 871251-66-0; Methyl 2-(4-trifluoromethylphenyl)pyrimidine-5-carboxylate; 2-(p-Trifluoromethylphenyl)-5-pyrimidinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethylphenyl)Pyrimidine-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.