Description

7-(4-Fluorophenyl)-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its fused triazolopyrimidine heterocyclic core. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Integral in the process development and scale-up of potential new active pharmaceutical ingredients, especially those containing fluorinated heterocycles.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical companies with custom synthesis and process optimization.
• Biochemical Research: May be employed as a tool compound or inhibitor in biochemical assays to study specific enzyme or receptor interactions.

Basic Information

Product Name	7-(4-Fluorophenyl)-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylic Acid
CAS No.	871233-87-3
Molecular Formula	C13H9FN4O2
Molecular Weight	272.24 g/mol
Synonyms	7-(4-Fluorophenyl)-4,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid; 4,7-Dihydro-7-(4-fluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic Acid; [1,2,4]Triazolo[1,5-a]pyrimidine-5-carboxylic acid, 7-(4-fluorophenyl)-4,7-dihydro-; 871233-87-3; 7-(p-Fluorophenyl)-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidine-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 7-(4-Fluorophenyl)-4,7-Dihydro[1,2,4]Triazolo[1,5-A]Pyrimidine-5-Carboxylic Acid adheres to stringent quality management protocols. Each batch is manufactured under controlled conditions and undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.